Abstract

Purpose: While exercise is recommended as the first-line intervention for people with chronic knee pain due to osteoarthritis (OA), a significant proportion of individuals do not respond to exercise interventions and may even report more pain. A normal response to a bout of exercise is characterized by reductions in pain and pain threshold, a phenomenon known as exercise induced hypoalgesia (EIH). Some individuals with chronic pain show an impaired EIH response immediately after exercise which may contribute to non-response after exercise interventions.

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