Abstract
7055 Background: Obesity, body mass index (BMI) ≥30 kg/m2, is a risk factor for several malignancies. Prospective studies have reported a positive association between obesity and adult leukemia. The association between obesity and AML cytogenetic risk groups is unknown. We therefore evaluated a cohort of 295 AML patients with confirmed cytogenetics analysis diagnosed and treated at Mayo Clinic Florida and Arizona since 1995. Methods: Documented patient characteristics including height and weight, past medical history, medications, cytogenetics, treatments, and outcomes regarding their diagnosis of AML were extracted from a central electronic medical record. Standard cytogenetic risk categories (including intermediate abnormal) were applied. The association of obesity with cytogenetic risk was evaluated on multivariable analysis using logistic regression models. Results: The median BMI was 26.9 kg/m2 (range 16.9-59.9). 82 patients (28%) in the evaluated cohort were obese. On multivariable analysis obesity ...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
