Abstract
BackgroundThis study aimed to retrospectively analyze the correlation between congenital abnormality of the urogenital system and various factors in children with neural tube defects (NTDs).MethodsA total of 190 children with congenital NTDs, who were admitted to a hospital from May 2013 to May 2018, were included into the present study. All admitted children with congenital NTDs were carried out routine abdominal B-ultrasound examinations to determine the malformations of the abdominal organs, including the urinary system. Children with a B-ultrasound result of suspected and unsure malformation underwent intravenous pyelography (IVP) and voiding cysto-urethrography (VCU), and this was further confirmed by the CT results.ResultsThe incidence of urogenital malformation was 12.1% (23/190) in children with congenital NTDs. For the 23 children with urogenital malformations, most of these children had no definite urinary system symptoms, while some of these children had multiple incidences of urinary system infections.ConclusionsCongenital NTDs are often combined with urogenital malformations, if not specifically searched these may be overlooked. The early detection of these malformations is beneficial to reduce the risk of operation and improve the prognosis.
Highlights
This study aimed to retrospectively analyze the correlation between congenital abnormality of the urogenital system and various factors in children with neural tube defects (NTDs)
All children underwent routine abdominal Bultrasound at admission to determine the condition of the abdominal organs, including the urogenital system, received routine X-ray, computed tomography (CT) and magnetic resonance imaging (MRI) to identify the NTDs, and received an electrocardiogram to determine whether the heart was abnormal
Since May 2013, the Neurosurgery Department of our hospital began to carry out routine abdominal Bultrasound examinations for all admitted children with congenital NTDs, in order to determine the malformations of the abdominal organs, including the urinary system
Summary
This study aimed to retrospectively analyze the correlation between congenital abnormality of the urogenital system and various factors in children with neural tube defects (NTDs). Neural tube defects (NTDs), which are known as dysrhaphia, are congenital malformations caused by the failure of closure of the neural tube during its development. This can be divided into two types: open type and closed type [1]. Congenital NTDs are often combined with other systemic malformations. Hunt and Whitaker in 1987 and Sally-Anne Hulton in 1990 reported that the incidence of renal malformation in children with congenital. NTDs was 8.9% and 10.4% [3, 4], respectively This has aroused the clinical attention of researchers to congenital NTDs combined with urogenital malformation. The early detection of concomitant malformations and the development of an appropriate treatment plan would help to reduce the potential risk of surgery, and help to improve the long-term prognosis of children [5]
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