Abstract
Objective: To find out association between Nasal polyposis and bronchial asthma.
 Methods: This was a cross sectional study which was carried out in the departments of Otolaryngology and Head-Neck surgery of Bangabondhu Sheikh Mujib Medical University and Dhaka Medical College Hospital during the period of February 2014 to July 2014. A Total 230 patients were selected according to selection criteria among which 30 subjects had nasal polyposis (designated as group A or cases) and 200 subjects had no nasal polyposis (designated as group B or control group).
 Results: In group (A), asthma was found in 30.0% cases. On the other hand, asthma was found in 2.5% of control group (B). The association of nasal polyposis with bronchial asthma was highly significant (p<.05). In both group 40.0% patients were within the 38-47 year’s age group. In case group, 80.0% patients had any sorts of allergic history on the other hand, only 15.0% patients had allergic history in control group. High eosinophil count was found 66.7% patients suffering from nasal polyposis with bronchial asthma and in comparison to patients suffering from nasal polyposis without bronchial asthma had high eosinophil count 42.85%. In group A High IgE level was found 66.7% patients suffering from nasal polyposis with bronchial asthma, on the other hand, 42.85% had IgE level among patients suffering from nasal polyposis without bronchial asthma.
 Conclusion: Patients with nasal polyposis and asthma are significantly associated. Both serum IgE and total circulating eosinophil count are significant associated with nasal polyposis and bronchial asthma.
 Bangladesh J Otorhinolaryngol; April 2017; 23(1): 11-18
Highlights
Nasal polyposis and bronchial asthma both are the diseases of respiratory system
We found some of the patients of nasal polyposis who are simultaneously suffering from bronchial asthma
Nasal polyposis consisting of recurrent, multiple polyps, is part of an inflammatory reaction involving the mucous membrane of the nose, paranasal sinuses and often the lower airways
Summary
Nasal polyposis and bronchial asthma both are the diseases of respiratory system. We found some of the patients of nasal polyposis who are simultaneously suffering from bronchial asthma. Bronchial asthma present before or after presentation of nasal polyposis or both the disease may simultaneously. It is described that there is a link between nasal polyposis and bronchial asthma. Nasal polyp is an oedematous mucous membrane which forms a pedunculating process with a slim or broad stalk or base which originate around the openings to the ethmoidal sinuses. Nasal polyposis consisting of recurrent, multiple polyps, is part of an inflammatory reaction involving the mucous membrane of the nose, paranasal sinuses and often the lower airways. Nasal polyposis is a disease of unknown aetiology.[1]
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