Association of mean platelet volume with ST-segment resolution in acute ST-segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention

Abstract

Objective To investigate the relationship between mean platelet volume and myocardial reperfusion in acute ST-segment elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention(PCI). Methods A total of 162 STEMI patients with primary PCI were enrolled in this study.The patients were divided into two groups according to ST-segment resolution(STR) at 2 h after PCI: STR≥50% group and STR<50% group, the MPV were compared.Predictors of poor STR were identified by multivariable logistic regression analysis. Results The patients with STR≥50% had significant higher MPV.In multivariable Logistic regression analysis, higher MPV before PCI was independently associated with STR≥50%.Other independent predictors were onset to balloon time, infarction related artery(LAD) and TIMI flow grade <Ⅲ after PCI. Conclusions Higher MPV is an independent predictor of poor myocardial reperfusion in STEMI patients after PCI. Key words: Acute myocardial infarction; Mean platelet volume; Myocardial reperfusion; ST-segment resolution