Association of Maternal Dietary Patterns during Pregnancy and Offspring Weight Status across Infancy: Results from a Prospective Birth Cohort in China.

Jiajin Hu,Izzuddin M Aris,Yilin Liu,Deliang Wen,Pi-I D Lin,Yinuo Wang,Ningyu Wan

doi:10.3390/nu13062040

Jiajin Hu, Izzuddin M Aris + Show 5 more

Open Access

https://doi.org/10.3390/nu13062040

Copy DOI

Journal: Nutrients	Publication Date: Jun 15, 2021
Citations: 2	License type: CC BY 4.0

Affiliation: China Medical University, Harvard University

Abstract

Literature on maternal dietary patterns during pregnancy and offspring weight status have been largely equivocal. We aimed to investigate the association of maternal dietary patterns with infant weight status among 937 mother–infant dyads in a Chinese birth cohort. We assessed maternal diet during pregnancy using food frequency questionnaires (FFQ) and three-day food diaries (TFD) and examined infants’ body weight and length at birth, 1, 3, 6, 8 and 12 months. Maternal adherence to the “protein-rich pattern (FFQ)” was associated with lower infant body mass index z-scores (BMIZ) at birth, 3 and 6 months and lower odds of overweight and obesity (OwOb) across infancy (quartile 3 (Q3) vs. quartile 1 (Q1): odds ratio (OR): 0.50, (95% confidence interval: 0.27, 0.93)). Maternal adherence to the “vegetable–fruit–rice pattern (FFQ)” was associated with higher BMIZ at birth, 3 and 6 months and higher odds of OwOb across infancy (Q3 vs. Q1: OR: 1.79, (1.03, 3.12)). Maternal adherence to the “fried food–bean–dairy pattern (TFD)” was associated with lower BMIZ at 3, 6, 8 and 12 months and lower odds of OwOb (Q3 vs. Q1: OR: 0.54, (0.31, 0.95)). The study results may help to develop interventions and to better define target populations for childhood obesity prevention.

Highlights

Childhood obesity remains a global public health concern [1,2,3], as childhood obesity often tracks into adulthood and is strongly associated with adult chronic diseases such as diabetes and metabolic syndrome [4,5]
Model 1: crude model, Model 2: adjusted for other dietary patterns derived from the same dietary assessment tool (TFD or food frequency questionnaires (FFQ)), Model 3: adjusted for prepregnancy body mass index (BMI), age, parity, family income, education level, ethnicity, smoking status, total calorie intake, physical activity, paternal BMI, Model 4: model 2 + model 3. In this prospective birth cohort in China, we observed some evidence that maternal adherence to dietary patterns characterized by higher protein intake (i.e., “protein-rich pattern (FFQ)” and “fried food–bean–dairy pattern (TFD)”) during pregnancy were associated with lower infant BMI z-score and lower likelihood of being overweight and obesity (OwOb) across infancy
We found several maternal dietary patterns that were associated with offspring weight status across infancy

Summary

Introduction

Childhood obesity remains a global public health concern [1,2,3], as childhood obesity often tracks into adulthood and is strongly associated with adult chronic diseases such as diabetes and metabolic syndrome [4,5]. Previous studies indicated that accelerated growth in early life, especially during infancy, is a strong risk factor for subsequent childhood obesity [6,7]. Identifying modifiable determinants of infant growth may provide insight into intervention strategies for childhood obesity prevention in early life. The recent report from the Commission of Ending Childhood Obesity [8] highlighted the importance of prenatal care, such as appropriate maternal nutrition during pregnancy, as a key modifiable factor and strategy in childhood obesity prevention.

Objectives

Methods

Results

Discussion

Conclusion