Abstract

Purpose: Walking and functional decline associated with knee osteoarthritis (OA) are significant, independent predictors of poor health state. Difficulty with stair ambulation can be an early response to pain and signal functional decline in individuals with or at risk for knee OA, resulting in asymmetrical movement patterns to reduce symptoms and compensate for associated muscle weakness. Lower limb strength asymmetry has been associated with increased odds of secondary OA development, with a 1% increase in quadriceps symmetry index (SI) resulting in a 4% lower odds of clinical OA development.

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