ASSOCIATION OF LIPID PROFILE AMONG THE HYPERTENSIVE IN COMPARISON TO NORMOTENSIVE PATIENTS IN OUR INSTITUTION

Abstract

Introduction: Hypertension and dyslipidemia are associated with oxidative stress and are major causes of cardiovascular disease amounting to 30% of global death rate. It is widely accepted that cardiovascular disease is associated with hypertension and increased blood levels of low-density lipoprotein (LDL), total cholesterol (TC), and triglycerides. In contrast, a low level of high density lipoprotein (HDL) is a risk factor for mortality from cardiovascular disease. Hypertension is a major public health problem in developed and developing countries. Methods: This study was a cross sectional study in which 159 diagnosed hypertensive patient and 75 with normal blood pressure (normotensive) were enrolled. These patients sought a through health cheek up including blood pressure assessment between May 2020 to April 2021 Results: The mean of Systolic blood pressure and Diastolic blood pressure of hypertensive were higher than normotensive (p<0.001). The serum levels of total cholesterol, triglyceride and LDL-C in hypertensive subject were higher than normotensive and statistically signicant (p<0.001). Serum HDL-C was signicantly lower (p<0.001) in hypertensive patients than in normotensive. Conclusion: Hypertensive patients have been found to have close association with dyslipidemia. Hypertensive patients need measurement of blood pressure and lipid prole at regular interval to prevent heart diseases and stroke