Abstract
The developing brain is marked by high plasticity which can lead to vulnerability to early life stressors, such as trauma. Trauma has been shown to affect brain structure and to increase the risk of developing psychopathology later in life. However, previous studies on the relationship between trauma and brain structure are limited by small sample size, case-control designs, and heterogeneous age groups. The present study aimed to investigate how trauma is associated with cortical thickness and gray matter volume (GMV) in the early developmental stage by leveraging a large sample of 9 to 10-year-old children (N=9,270) from the Adolescent Brain and Cognitive Development Study (ABCD Study).
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