Association of interleukin-6 (-174 G/C) polymorphism with the prostate cancer risk: A meta-analysis.

Abstract

OR, 3.51; 95% CI, 1.04-11.82; P=0.042) in African-American patients. However, no significant association was found in the Caucasian, Asian or mixed populations under the five genetic models by stratifying studies for ethnicity. In conclusion, the present study suggested that there was no significant association between the IL-6 (-174 G/C) polymorphism and prostate cancer risk in Caucasian and Asian patients, whereas the CC genotype may be associated with an increased risk in the African-American patients.