Abstract
H. pylori infection is strongly related with chronic gastritis of the stomach, which causes impairment in gastric acid and secretion of pepsin, and linked to male absorption of food-vitamin B12. The most important virulence genes accompanying stomach and intestine disease are (cag A and vac A). Aim of the study: To evaluate the rate of gastric ulcer infection with H. pylori and its detect CagA gene in H.pylori isolated from gastritis. Materials and Methods: A total of 200 biopsy patients aged from (10- ≥ 60) years were collected from Baqubah teaching hospitals. They were suffering from gastric upset and attended to endoscopic unit of department of medicine. Questioners including, sex, age, smoking, presence of cancer, and biopsies of gastric tissue were collected from the corpus or the ant rum or corpus and ant rum of the patient's stomach. Three biopsies were taken from each patient. Histopathologic study, gram staining, and rapid urease test working for each patients. Serology Test Serum Enzyme-Linked Immunosorbent Assay Testing (ELISA).
Highlights
Helicobacter pylori (H. pylori) affects nearly half of the world’s population, is one of the most frequent and persistent bacterial infections [1]
Vitamin B12 is an essential cofactor that is integral to methylation processes important in reactions related to DNA and cell metabolism, deficiency may lead to disruption of DNA and cell metabolism and have serious clinical consequences [23]
The deficiency of vitamin B12 is clinically manifested in the blood and nervous system where the cobalamin plays a key role in cell replication and in fatty acid metabolism [28]
Summary
Helicobacter pylori (H. pylori) affects nearly half of the world’s population, is one of the most frequent and persistent bacterial infections [1]. H. pylori infection plays an important role in the development of atrophic gastritis and related malabsorption. It is suggested that there may be a relationship between H. pylori infection and vitamin B12 deficiency [3]. During the period October 2006 to July 2007 a study was done by WHO which involve Isolation and identification of H. pylori from drinking water in Basra governorate, Iraq.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
