Association of HbA1c, serum uric acid and non HDL cholesterol in type 2 diabetes patients

Abstract

Dyslipidemia is an established marker for endothelial dysfunction and cardiovascular risk in diabetes. So we aimed to explore the prevalence of dyslipidemia in patients with type2 diabetes mellitus (DM) and to determine the association between dyslipidemia and other health care and biochemical indicators.A cross-sectional study was carried out at private health care center. A total of 291 diabetic patients aged 18 years and above attended the clinic from August 2017 through April 2018 were included. Socio-demographic, clinical, and laboratory data were obtained from the medical records of patients. Statistical analysis was carried out using (SPSS, version 23).out of the 291 diabetes patients recruited 22.3% had hypercholesterolemia (TC ≥ 200) and 61.9% had hypertriglyceridemia. Abnormal LDL-C levels (≥130) were found in 8.9% of patients and HDL-C was less than 40 mg/dl in 54.3%. There was a statistically significant difference (P = 0.048) in abnormal HDL levels (˂ 40 mg/dl) among females (59.3%) and males (47.6). Patients with HbA1c values ≥ 7.0%had significantly higher values of total cholesterol (TC) and abnormal LDL-C compared with the patients who had HbA1c ˂ 7.0%.dyslipidemia is highly prevalent among diabetic population particularly in those with poorly controlled diabetes. This calls for early and universal screening of lipid profile. There is also an urgent demand for measures that target tight glycemic, optimal lipid profile control and life style modifications is also required to all diabetic patients to achieve target value of HbA1C ≤ 7.