Abstract
We describe a Chinese patient who was heterozygous for both Hb Q-Thailand [α74(EF3)Asp→His] and Hb E [β26(B7)Gly→Asp, GAG→GTG]. Interaction of the αQ-Thailand and βE chains leads to a hemoglobin (Hb) variant, namely Hb QE, which differs in electrophoretic mobility and high performance liquid chromatography (HPLC) profiles and in the amount of the Hb Q-Thailand variant present in the blood.
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