Abstract

Objective: Aimed to find the cut-off point of handgrip strength and it’s association with MetS.Results: The relative handgrip strength was negatively associated with the prevalence of MetS. Of note, the odds ratios (ORs) with 95% confidence intervals (CIs) across tertiles of relative handgrip strength were 1 (reference), 0.45 (0.33, 0.62), and 0.13 (0.08, 0.20) in male participants after adjusting for demographic factors, calorie intake, and physical activity. Similar results were observed in female participants. The cutoff values of relative handgrip strength for male and female participants were 0.52 and 0.40, respectively.Conclusions: Findings of this study suggest that a strong relationship exists between handgrip strength and prevalence of MetS in US adults, regardless of sex.Methods: A total of 5 056 participants in the National Health and Nutrition Examination Survey were analysed in this study. Handgrip strength was measured by using a handgrip dynamometer. MetS was defined in accordance with the criteria of the scientific statement of the American Heart Association in 2009. Multivariable binary logistic regression was used to explore the association between handgrip strength and MetS.

Highlights

  • Metabolic syndrome (MetS) is a group of metabolic conditions that occur together and promote the development of cardiovascular disease and diabetes [1]

  • According to the data from National Health and Nutrition Examination Survey (NHANES) 2011-2012 and 2013-2014 cycles, 19 931 people joined the household questionnaire interview, and 14 984 people participated in the handgrip strength test

  • The cut-off values of relative handgrip strength were 0.52 and 0.40 for male and female participants, respectively. In this cross-sectional study, we explored the associations between handgrip strength and MetS in general United States (US) adults

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Summary

Introduction

Metabolic syndrome (MetS) is a group of metabolic conditions that occur together and promote the development of cardiovascular disease and diabetes [1]. Inhibition of myostatin suppresses body fat accumulation and www.aging-us.com improves insulin sensitivity [17, 18]. These myokines appear to participated in maintenance of whole-body metabolic homeostasis. Several previous studies found that high muscle strength was associated with lower prevalence of MetS [23,24,25,26,27,28,29,30]. In the US, only the Aerobics Center Longitudinal Study demonstrated that lower muscle strength was associated with higher MetS prevalence in men [30].

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