Abstract
Objective: To see the association of gallstones with gallbladder carcinoma and its prevalence in patients undergoing surgery for cholelithiasis. Methods: This cross-sectional observational study was conducted from July 2012 to June 2013 at the Department of Surgery, Mymensingh Medical College Hospital, Mymensingh with 150 cases of cholelithiasis. Results: Of 150 cases those were operated for gall bladder stone disease, 8 (eight) were found to have carcinoma of gall bladder i.e. prevalence was 5.3%. On ultrasound, only three (37.5%) patients were suspected as gall bladder carcinoma pre-operatively. Females are more affected than males by this disease. Also gall bladder carcinoma was found to be associated with single large-sized stone. Conclusion: The ultrasonography can miss a significant number of malignant lesions of the gall bladder in early stages and every cholecystectomy specimen should be examined histologically. Mediscope 2021;8(2): 87-93
Highlights
Gall bladder carcinoma is uncommon, but it is the third most common malignancy of gastrointestinal tract and the most common malignancy of biliary tract.[1]
During the study period all patients with cholelithiasis admitted in different surgical units of Mymensingh Medical College Hospital with all ages and sexes were included but acalculous cholecystitis, patients who refused operative treatment and those unwilling to participate in the study were excluded
Signs and symptoms of gall bladder carcinoma were generally indistinguishable from those associated with cholecystitis and symptomatic cholelithiasis
Summary
Gall bladder carcinoma is uncommon, but it is the third most common malignancy of gastrointestinal tract and the most common malignancy of biliary tract.[1].
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