Abstract

Association of Edmonton Symptom Assessment System Global Distress Score With Overall Survival in Patients With Advanced Cancer

Highlights

  • Despite compelling data supporting their use, patient reported outcomes (PROs) are not widely integrated into routine cancer care.1 Given the landscape of PRO instruments with convoluted scoring methods, we reflected on our own PRO-driven palliative care (PC) practice, where over the past 20 years all patients completed the Edmonton Symptom Assessment System (ESAS) at every visit

  • A higher Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) was associated with higher Global Distress Score (GDS) in this

  • While a higher ECOG PS was associated with having a higher GDS, obtaining the ESAS presents an opportunity for the clinical team to intervene on specific symptoms that contribute to an individual patient’s symptom burden and suffering

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Summary

Introduction

Despite compelling data supporting their use, patient reported outcomes (PROs) are not widely integrated into routine cancer care. Given the landscape of PRO instruments with convoluted scoring methods, we reflected on our own PRO-driven palliative care (PC) practice, where over the past 20 years all patients completed the Edmonton Symptom Assessment System (ESAS) at every visit. Despite compelling data supporting their use, patient reported outcomes (PROs) are not widely integrated into routine cancer care.. Given the landscape of PRO instruments with convoluted scoring methods, we reflected on our own PRO-driven palliative care (PC) practice, where over the past 20 years all patients completed the Edmonton Symptom Assessment System (ESAS) at every visit. As a simple, validated 10-item PRO tool, the ESAS measures the following 10 common symptoms in advanced illness: pain, fatigue, nausea, drowsiness, appetite, dyspnea, well-being, anxiety, depression, and sleep (Figure 1).. Validated subscales of the ESAS include the Global Distress Score (GDS), a sum of the first 9 physical and psychosocial ESAS symptoms.. We examined the association between the ESAS and overall survival (OS) in patients with advanced cancers. As a simple, validated 10-item PRO tool, the ESAS measures the following 10 common symptoms in advanced illness: pain, fatigue, nausea, drowsiness, appetite, dyspnea, well-being, anxiety, depression, and sleep (Figure 1). Validated subscales of the ESAS include the Global Distress Score (GDS), a sum of the first 9 physical and psychosocial ESAS symptoms. In this study, we examined the association between the ESAS and overall survival (OS) in patients with advanced cancers.

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