Association of Echocardiographic Parameters and Outcomes in Patients with Heart Failure with Reduced Ejection Fraction who Have an Implantable Remote Pulmonary Artery Hemodynamic Monitoring System

Abstract

Background Remote pulmonary artery (PA) hemodynamic monitoring with CardioMEMS device has shown to decrease heart failure (HF) admissions in patients with heart failure with reduced ejection fraction (HFrEF). The aim of our study was to evaluate the relationship between echocardiographic variables that are associated with cardiac remodeling and outcomes in patients with HFrEF who had CardioMEMS device implant. Methods Retrospective data was collected for patients who had transthoracic echocardiography done prior to CardioMEMS device implantation for HFrEF. Favorable outcomes was defined as a decrease in 1-year HF admissions post-CardioMEMS implantation, unfavorable outcomes was defined as no decrease or increase in 1- year HF admissions post-implantation. Echocardiographic parameters were compared between the two groups using the independent t-test. Results We identified 48 patients with HFrEF who had CardioMEMS device during the study period. Pre-echocardiographic parameters like left atrial volume (LAV), LAV index, left ventricle (LV) end-diastolic volume, LV diastolic diameter, LV systolic diameter, LV mass were all greater in patients with unfavorable outcomes. But only difference in LV diastolic diameter between the groups was significant. Conclusion Patient with HFrEF who had favorable outcomes after CardioMEMS device implantation had lower LV end-diastolic diameter compared to patients with unfavorable outcomes.