Abstract
Analysis of the association between several DNA repair gene polymorphisms and the level of chromosomal aberrations (CAs) in lymphocytes of two groups of adolescents was carried out: in a group of 256 donors exposed to indoor radon and a control group of 94 donors. In a group of children with living conditions exposing them to high doses of radon (>200 Bq/m3), the level of CAs was significantly higher among carriers of genotypes hOGG1 Cys/Cys, hOGG1 Ser/Cys, ADPRT Ala/Ala, and ADPRT Val/Ala. No significant association between the level of CA and XRCC1 Arg194Trp, XRCC1 Arg280His, XRCC1 Arg399Gln, and APE1 Asp148Glu polymorphisms was found.
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