Abstract

Background and objectivesTo explore the relationship between dietary patterns, physical activity and lipid-related indices in Chinese Population.Methods and study designThis study included 21,472 (72.3% men) participants aged 16 to 78 years. Data of anthropometric measurements, biochemical tests and questionnaires were collected through a physical examination. Diet patterns were identified through factor analysis and five patterns were retained (“meat,” “high-energy,” “high-protein,” “healthy” and “traditional Chinese”). Physical activity was classified into low, moderate, or high. Abnormalities in lipid indices were assessed using the Adult Treatment Panel III criterion.ResultsHigher factor scores of “high-protein” pattern and “healthy” pattern were found to be related to favorable lipid indices. Quartiles 3 and 4 of “meat” pattern showed increased risks of having elevates total cholesterol and low-density lipoprotein cholesterol concentrations. Participants with higher levels of physical activity showed lowest risk of abnormal lipid profiles. All the associations were equally established among men, while most were no longer significant among women.ConclusionsHigher physical activity level and a dietary pattern consists of high-quality protein foods, vegetables and fruits were associated with favorable lipid profiles, and these lifestyle factors were related to the risk of dyslipidemia in a sex-specific way.

Highlights

  • Dyslipidemia has become an important public health problem worldwide due to its risk of development of cardiovascular diseases and high prevalence [1,2,3]

  • Higher physical activity level and a dietary pattern consists of high-quality protein foods, vegetables and fruits were associated with favorable lipid profiles, and these lifestyle factors were related to the risk of dyslipidemia in a sex-specific way

  • Alcohol drinking was observed to be associated with elevated risk of Total cholesterol (TC) abnormalities and decreased risk of highdensity lipoprotein cholesterol (HDL-C) abnormalities, while the relationship was different across genders in terms of the risk of TG abnormalities

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Summary

Introduction

Dyslipidemia has become an important public health problem worldwide due to its risk of development of cardiovascular diseases and high prevalence [1,2,3]. The Dietary Approaches to Stop Hypertension which recommended a diet to consume more fruits and vegetables and limited in saturated fats and cholesterol products has been proven to be beneficial to low-density lipoprotein cholesterol (LDL-C) level [8, 9]. Physical activity (PA) has been proven to be beneficial to lipid profiles by elevate highdensity lipoprotein cholesterol (HDL-C) and lowering triglyceride (TG) levels [12,13,14], and its mechanism may be due to the improvement of endothelial function [15]. To explore the relationship between dietary patterns, physical activity and lipidrelated indices in Chinese Population

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