Association of breast cancer with sleep pattern--a pilot case control study in a regional cancer centre in South Asia.

Karabi Datta,Dipanwita Ghosh,Subhas Guha,Ila Das,Samar Sikdar,Jaydip Biswas,Durgaprasad Nanda,Asoke Roy

doi:10.7314/apjcp.2014.15.20.8641

Abstract

The rising trend of breast cancer both in developed and developing countries is a real threat challenging all efforts to screening, prevention and treatment aspects to reduce its impact. In spite of modern preventive strategies, the upward trend of breast cancer has become a matter of great concern in both developed and developing countries. Chittaranjan National Cancer Institute is a premier regional cancer institute in eastern region of India catering to a large number of cancer patients every year. A pilot case control study of fifty breast cancer patients and 100 matched controls was conducted during 2013 to evaluate the effects of habitual factors like working in night shift, not having adequate sleep, and not sleeping in total darkness on breast cancer of women. The study revealed that not sleeping in total darkness was associated with higher odds of outcome of breast cancer of women. This positive correlation can play a vital role in formulation of preventive strategies through life style modification.

Highlights

U.S Cancer Statistics Working Group (2013) shows that in 2010. 206,966 women and 2,039 men in the United States were diagnosed with breast cancer and 40,996 women and 439 men in the United States died from breast cancer
A pilot Case Control study was conducted in Chittaranjan National Cancer Institute, Kolkata, India during the period 2013 to evaluate the effects of multiple explanatory factors on a binary outcome variable, i.e., effects of habitual factors like working in night shift, not having adequate sleep, not sleeping in total darkness on breast cancer of women
Three factors were considered in this study, namely, having adequate sleep, not sleeping in total darkness and working at night shift

Summary

Introduction

U.S Cancer Statistics Working Group (2013) shows that in 2010. 206,966 women and 2,039 men in the United States were diagnosed with breast cancer and 40,996 women and 439 men in the United States died from breast cancer. Farley et al (2010) find cancer of the breast in women is a major health burden worldwide It is the most common cause of cancer among women in both high-resource and low-resource settings, and is responsible for over one million of the estimated 10 million neoplasm diagnosed worldwide each year in both sexes. It is the primary cause of cancer death among women globally, responsible for about 375,000 deaths in the year 2000. Ferlay et al (2010) showed that in 2008 in 40 European countries, the most common cancers were colorectal cancers (13.6% of the total) followed by breast cancer (13.1%), lung cancer (12.2%).The most common causes of death from cancer were lung cancer (19.9% of the total), colorectal cancer (12.3%), breast cancer (7.5%) Up-to-date statistics on cancer occurrence and outcome are essential for the planning and evaluation of programmes for cancer control

Methods

Results

Conclusion