Abstract

Chiang HL, Liu CJ, Hu YW, Chen SC, Hu LY, Shen CC, et al. Risk of cancer in children, adolescents, and young adults with autistic disorder. J Pediatr. 2015;166:418-23. Among children and adolescents, what is the association of autistic disorder (AD) with cancer? Retrospective cohort study. Taiwan National Health Insurance Research Database, Registry for Catastrophic Illness Patients. Children and adolescents with AD enrolled in the databases from 1997 through 2011 at ages 1-20 years. Analysis of database and registry. Number of cancers in patients with AD compared with the expected number. Cancer occurred more frequently in patients with AD than the total number of expected cancers, with a standardized incidence ratio (SIR) estimate (number of AD patients with cancer divided by the expected number) of 1.94 (95% CI 1.18-2.99). Patients with AD have an increased risk of cancer.

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