Abstract
The purpose of the present study was to investigate the predictive role of apolipoprotein E genotypes for stroke-related risk factors in the Turkish population. Among 100 stroke patients and 30 healthy subjects included in the study, most frequent Apo E genotype was ε3/3, compatible with polymorphic distribution of Asian population. VLDL and triglyceride levels in ε2/4(+) subjects were higher than in ε2/4(−) patients. HDL and homocysteine levels were higher in ε4/4 (+) subjects than in ε4/4 (−) stroke patients. These results suggest that ApoE polymorphism in this population was not associated with any other demographic or clinical variables except for lipid profiles and homocysteine levels.
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