Abstract
Aims: This study aimed to investigate the lipids profile, APOA genotype with malaria infection. It was hypothesized that the malaria parasite uses cholesterol and phospholipids from its host, resulting in a decrease in serum HDL.
 Study Design: A cross-sectional hospital -based study. 
 Place and Duration of Study: The study was conducted during the transmission season between July to November 2020 in different hospitals and centers in Elfasher city.
 Methodology: We included (39 men and 64 female), 57.3% were adults and 42.7% were children, plasmodium falciparum infection, with clinical symptoms and signs of uncomplicated malaria. Parasites density, lipids profile and APOA genotyping were assayed.
 Results: The mean level of CHOL and TG was 134.7 mg/dl and 73.0 mg/dl, respectively, and the average levels of LDL and HDL are 56.6 mg/dl and 56.2 mg/dl, respectively. The G/G genotypes of APOA were identified in 94.2% of the patients compared to other APOA genotypes. The overall allele frequency for the G allele was 96.0%, and the T allele was 3.9% using the Hardy-Weinberg distribution.
 Conclusion: In conclusions, the lipids profile and APOA genotype were not associated with uncomplicated malaria.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
