Association of Alcohol Consumption with Impaired Beta-Cell Function Independent of Body Mass Index Among Indian Men

Abstract

Heavy alcohol consumption is linked to the development of type 2 diabetes. Alcohol's effects on the function of cells are not completely known at this time. This investigation looked into the relationships that exist between all of these different characteristics. All of the males who participated in this study were of Indian descent, and their ages ranged anywhere from 25 to 80 years old. Participants were categorized as abstainers, teetotalers, light drinkers (drinking between 0.1 and 20 grams of alcohol per day), moderate drinkers (consuming between 21.0 and 40 grams of alcohol per day), or heavy drinkers (consuming more than 41 grams of alcohol per day). Light drinkers consumed between 0.1 and 20 grams of alcohol per day. Moderate drinkers consumed between 21.0 and 40 kilos of alcohol per day. Heavy drinkers used more than 41 grams of alcohol per day. After that, the participants were separated into two groups: those with a body mass index (BMI) of less than 25 kilograms per square meter and those with a BMI of 25 kilograms per square meter or more. A number of parameters, such as age, smoking status, body mass index (BMI), waist circumference, blood pressure, lipids, and serum uric acid levels, were taken into consideration. In comparison to individuals who refrained from alcohol use, those who drank alcohol had a lower HOMA- score, and this was the case independent of their body mass index. In the group with a BMI of less than 25 \(kg/m^{2}\), both past and current alcohol use were substantially connected with HOMA-IR. However, this association was not seen in the group with a BMI of more than 25 \(kg/m^{2}\). According to the results of multiple research, drinking alcohol is associated with -cell dysfunction in boys of Indian heritage, independent of the BMI of the participants in the studies.