Abstract
Background Left ventricular (LV) parameters may vary with aging, but concomitant disease can obscure relationships between age and LV size, mass and function. CMR provides reproducible measures of LV volumes, mass, and ejection fraction (EF), but manual analyses are time consuming. Automated border detection (ABD) methods may decrease analytical burden. We sought to examine the effect of greater age on LV volumes, mass, EF and concentricity in a large cohort of healthy adults free of clinical cardiovascular disease and hypertension using ABDassisted methods.
Highlights
Left ventricular (LV) parameters may vary with aging, but concomitant disease can obscure relationships between age and LV size, mass and function
Men had greater LV volumes, mass and concentricity than women (p
As the Table shows, LV EDV, end-systolic volume (ESV), and stroke volume (SV) decreased with greater age in both sexes; LV mass decreased with age in women but not men
Summary
Association of age with left ventricular volumes, ejection fraction and concentricity: the Framingham heart study. Michael L Chuang1,2*, Philimon Gona, Gilion Hautvast, Carol J Salton, Marcel Breeuwer, Christopher J O’Donnell, Warren J Manning. From 16th Annual SCMR Scientific Sessions San Francisco, CA, USA. From 16th Annual SCMR Scientific Sessions San Francisco, CA, USA. 31 January - 3 February 2013
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