Association of adiponectin gene polymorphism and cytokines levels in obese patients with COVID-19

Abstract

Covid-19 is a genus of enveloped, positive-sense, single-stranded RNA viruses with a high degree of genetic diversity. They induce a variety of disorders affecting the respiratory, gastrointestinal, hepatic, and nervous systems in humans and animals, with different manifestation and severity. Several risk variables, including older age, male gender, type 2 diabetes mellitus, hypertension, coronary artery disease, and obesity (a higher body mass index (BMI)), are known to predict a worse course of covd-19 infection. Obesity is the result of the accumulation of an excessive amount of fat in the body and the condition arises from an imbalance between the amount of energy stored by increased food intake and the amount of energy expended as physical activity. The aims of study evaluate the effect of covid-19 on cytokines levels in obese patients. As well as, study the association of adiponectin gene polymorphism to the risk of infection with covid-19 in obese patients.