Abstract

Acute optic neuritis is characterized by thinning of the inner retinal layers on optical coherence tomography. Acute macular neuroretinopathy is an outer retinal disorder that leads to thinning of the outer nuclear layer. A 34-year-old woman experienced decreased bilateral visual acuity 1 day following the coronavirus disease 2019 infection. Brain magnetic resonance imaging and demyelination testing revealed mild-to-moderate uneven enhancement of bilateral optic nerve segments, with anti-mog antibody reactivity. Hormone therapy was initiated, which led to outer nuclear layer thinning, completion of the ellipsoid zone, and an absent chimeric zone. The patient’s vision had been fully restored at her 1-year follow-up.

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