Abstract
Objective: To determine the association between mortality and type 2 diabetes mellitus (T2DM) in older adults with cardiovascular disease by adjusting a T2DM model with glycated hemoglobin (HbA1c). Materials and methods: A retrospective cohort study conducted with a secondary database analysis of the original article entitled “Prevalence and Factors Associated with Frailty Among Peruvian Older Adults.” No sample size calculation was performed because the research used the data from the participants who met the inclusion criteria. Results: Older adults with T2DM have 10 % more risk of mortality than those who do not have T2DM. The highest frequency of mortality occurred in men. The greater the number of comorbidities, the higher the risk of mortality. After applying the Cox proportional hazards model to the research, the most significant risk factors for mortality were frailty and the number comorbidities. Conclusions: T2DM was a risk factor for mortality in older adults with cardiovascular disease in all the models. Additionally, there were other important variables whose impact was directly proportional to the mortality rate in our population and statistically stood out, such as the number of comorbidities and frailty, while the history of tobacco consumption was not significant.
Highlights
Factors Associated with Frailty Among Peruvian Older Adults (11) realizado del año 2010 al 2015 en el distrito de Bellavista-Callao, Perú, en el cual se siguieron por cinco años a 1896 adultos mayores del Servicio de Geriatría del Centro Médico Naval del Perú
Relation of smoking with total mortality and cardiovascular events among patients with diabetes mellitus: a meta-analysis and systematic review
Summary
Verónica Huamán Macha* 1,a; Alesandra Herrera Pandal 1,a; Fernando M. Objetivo: Determinar la asociación entre mortalidad y diabetes mellitus tipo 2 (DM2) en adultos mayores con enfermedad cardiovascular y realizar el análisis ajustando la DM2 con hemoglobina glicosilada (HbA1c). Resultados: En los adultos mayores con DM2 el riesgo de mortalidad es 10 % mayor que en los pacientes sin DM2. Luego de realizar la regresión de Cox, los factores de riesgo para mortalidad de mayor importancia fueron fragilidad y número de comorbilidades. Conclusiones: La DM2 es un factor de riesgo para mortalidad en adultos mayores con enfermedad cardiovascular en todos los modelos. Además existen otras variables importantes las cuales tienen un impacto directamente proporcional sobre la mortalidad de nuestra población y sobresalen estadísticamente como lo son el número de comorbilidades y la fragilidad, mientras que el antecedente de consumo de tabaco no es significativo. Palabras clave: Diabetes mellitus; Mortalidad; Enfermedades cardiovasculares; Anciano; Geriatría (Fuente: DeCS BIREME)
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