Abstract
Diabetes mellitus as the most prevalent metabolic disease is a multifactorial disease which is infuenced by environmental and genetic factors. In this systematic review, we assessed the association between genetic variants and diabetes/its complications in studies with Iraqi populations Conducted in this study was to investigate the possible role TCF7L2 rs7903146 (C/G) variant on susceptibility of T2DM among Iraqi type 2 diabetic patients with nephropathy complications and its relations with some type of kidney biomarkers. This case-control study included 100 T2DM patients and 100 patient with kidney failure 100 healthy person (control group). The results confrm the association between the TCF7L2 rs7903146 polymorphism and increase risk for type 2 diabetes in Iraqi an populations.
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