Abstract

Objective To determine the relationship between subclinical hypothyroidism (SCH) and the prevalence of albuminuria in type 2 diabetes mellitus.Methods A total of 826 type 2 diabetes mellitus patients without thyroid disease were enrolled.Participants were evaluated for glycemic control,thyroid function,and albuminuria in a cross-sectional analysis.Results Of 826 type 2 diabetes mellitus,780 subjects were euthyroid(94.44%,780/826) and 46 had SCH (5.56%,46/826).The patients with SCH had a higher proportion in women and higher body mass index compared with the patients with euthyroid [69.6%(32/46) vs.49.7%(388/780),(26.7 ± 4.0) kg/m2 vs.(25.1 ± 3.8) kg/m2],and there was significant difference(P < 0.01).No significant difference in glycated hemoglobin and the prevalence of albuminuria was found between the patients with SCH and the patients with euthyroid (P > 0.05).Conclusion SCH is not a risk factor for albuminuria in type 2 diabetes mellitus. Key words: Hypothyroidism;  Diabetes mellitus,type 2;  Albuminuria

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