Abstract

IntroductionShort or long sleep duration is a risk factor for cardiovascular disease, but the association between sleep duration and cardiovascular health is unclear. Our objective was to quantify the association between sleep duration and ideal cardiovascular health (CVH) in US adults. We hypothesized that very short (<6 h) and very long (≥9 h) sleep duration were associated with poorer CVH compared with sleep lasting 7 to <8 hours.MethodsWe conducted a cross-sectional evaluation of the nationally representative National Health and Nutrition Examination Survey in 2 cycles (2013–2014 and 2015–2016). Participants were 7,784 cardiovascular disease–free US adults aged 20 to 75. Self-reported sleep duration was categorized as <6 hours, 6 to <7 hours, 7 to <8 hours, 8 to <9 hours, and ≥9 hours. The American Heart Association’s ideal CVH metrics were used to determine the number of ideal CVH components, dichotomized as ideal (5–7 components) or not ideal (0–4 components). Survey-weighted logistic and linear regression models were used to determine the association between sleep duration and ideal CVH.ResultsThe weighted prevalences of those who slept 7 to <8 hours were 30.4%, very short sleep duration (<6 h), 9.0%, and very long duration (≥9 h), 13.5%. Only 21.3% of the population had ideal CVH. Compared with 7 to <8 hours, very short duration (OR = 0.65; 95% confidence interval [CI], 0.47–0.90) and very long duration (OR = 0.72; 95% CI, 0.55–0.94) were associated with decreased odds of ideal CVH. We confirmed findings by using linear regression.ConclusionsVery short and very long sleep duration were associated with decreased odds of ideal CVH and lower mean CVH scores. Future research should focus on clarifying causal associations between sleep duration and ideal CVH.

Highlights

  • Short or long sleep duration is a risk factor for cardiovascular disease, but the association between sleep duration and cardiovascular health is unclear

  • Our objective was to quantify the association between sleep duration and ideal cardiovascular health (CVH) in Conclusions Very short and very long sleep duration were associated with decreased odds of ideal CVH and lower mean CVH scores

  • Future research should focus on clarifying causal associations between sleep duration and ideal CVH

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Summary

Introduction

Short or long sleep duration is a risk factor for cardiovascular disease, but the association between sleep duration and cardiovascular health is unclear. Meta-analyses show a Ushaped association between short and long sleep duration and risk of developing cardiovascular disease (CVD) [4,5,6]. Potential mechanisms for this association with short sleep include dysregulation of appetite hormones [7], glucose intolerance [4], the upand-down regulation of gene expression [8], and circadian rhythm misalignment [9], which may result in inflammatory conditions and development of other CVD risk factors such as hypertension [10,11]. Meeting the ideal criteria for 5 to 7 components is associated with a reduced risk of developing CVD [14,15]

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