Association between simple test assessing hand dexterity and mild cognitive impairment in independent older adults.

Abstract

This study aimed to clarify the association between hand function, including grip strength and hand dexterity, assessed using snap fasteners, and mild cognitive impairment (MCI) in older adults with normal global cognitive function. A total of 228 functionally independent older adults (mean age 77.7±6.1years) participated in this study. None of the participants had a history of dementia diagnosis, and all the participants had a Mini-Mental State Examination score of ≥24. Participants were evaluated for hand function using grip strength and snap fastener tests, and for cognitive function using the National Center for Geriatrics and Gerontology-Functional Assessment Tool. A total of 72 participants (31.6%) were diagnosed with MCI. The slow snap fastener test group had a higher proportion of participants with MCI (p<0.001) and impairments in memory (p=0.010), attention (p=0.043), executive function (p<0.001), and processing speed (p=0.044) compared to the fast snap fastener test group. The slow speed of fastening snap fasteners was significantly associated with MCI and impairment in memory, attention, executive function, and processing speed (MCI: adjusted odds ratio (AOR)=3.88, 95% confidence interval (CI)=1.64-9.19; memory: AOR=5.73, 95% CI=1.58-20.82; attention: AOR=3.95, 95% CI=1.10-14.11; executive function: AOR=7.22, 95% CI=1.78-29.24; processing speed: AOR=7.52, 95% CI=1.19-47.66) according to the multiple logistic regression analysis. Grip strength was not significantly associated with cognitive impairment. Thus, hand dexterity assessed using the snap fastener test was associated with MCI in older adults with normal global cognitive function. Hand dexterity assessment using the snap fastener test is useful for detecting MCI in apparently healthy older adults.