Abstract
Objective To explore the association of serum UA level with the severity of coronary artery disease (CAD) assessed by different methods. Methods Five-hundred and fifteen patients with suspected CAD received coronary angiography and were divided into normal group and CAD group; the severity of CAD was assessed based on the SYNTAX score and the number of stenosis. Serum UA levels were compared between the normal and CAD group with different severity. Results The average UA level in high-risk group for SYNTAX score was significantly higher than that of in the normal, low-risk, or moderate-risk group; UA level did not differ significantly among the normal group and univessel disease, twovessel disease, and multi-vessel disease groups. Conclusions CAD patients with hyperuricemia have higher SYNTAX wores than those with normal serum UA level. Uric ac id is independently assoc iated with the severity of CAD. But this association can not he found as the severity of CAD was determined by the number of stenotic vessels. Key words: Uric acid; Coronary artery disease; Risk factor; SYNTAX score
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