Association between second-trimester bacterial invasion of amniotic fluid and spectrophotometry at 450 nm

Abstract

Discolored amniotic fluid has long been associated with poor pregnancy outcome.1, 2 Recently Sepulveda et al. found significant correlations between intraamniotic bleeding evidenced by an abnormal amniotic fluid optical density (OD) reading at 410 nm, increased fetal bowel echogenicity, and fetal aneuploidy (Sepulveda W, Reid R, Nicolaidis P, Prendiville O, Chapman RS, Fisk NM. Second-trimester echogenic bowel and intraamniotic bleeding: association between fetal bowel echogenicity and amniotic fluid spectrophotometry at 410 nm.