Abstract
Justificativa e objetivo: A DPOC é caracterizada pela limitação progressiva do fluxo aéreo associada a uma resposta inflamatória. O objetivo do estudo foi avaliar a influência e a associação das variáveis respiratórias sobre a capacidade de exercício em portadores de DPOC. Métodos: Estudo transversal avaliou 39 portadores de DPOC para obtenção do volume expiratório forçado no primeiro segundo (VEF1) e a capacidade vital forçada (CVF). A força muscular respiratória (FMR) avaliada em seus componentes de pressão inspiratória máxima (PImax) e pressão expiratória máxima (PEmax). Capacidade de exercício avaliada pelo Teste de Caminhada de Seis Minutos (TC6m) e Incremental Shuttle Walking Test (ISWT). Resultados: O VEF1 (% 39,8±15,3) e CVF (% 60,2±17,1) se encontram reduzidos em relação ao predito classificando-os em estadiamento grau II (21%), III (51%) e IV (28%). A PImax (92,7±14,6 % predito) e PEmax (97,6±19,0 % predito) se encontram dentro dos valores previsto para os sujeitos. Evidenciada correlação moderada entre a distância percorrida no ISWT vs VEF1 (r=0,35; p=0,02) e ISWT vs CVF (r=0,42; p
Highlights
Chronic Obstructive Pulmonary Disease (COPD) is characterized by progressive airflow limitation associated with an inflammatory response to harmful particles and gases, mainly caused by smoking.[1]
Data are presented as mean ± SD and median; n (%): number sample; ); COPD: Chronic Obstructive Pulmonary Disease; body mass index (BMI): Body Mass Index; Respiratory muscle strength (RMS): Respiratory Muscle Strength; maximal inspiratory pressure (MIP): Maximum Inspiratory Pressure; maximal expiratory pressure (MEP): Maximum Expiratory Pressure; forced vital capacity (FVC): Forced Vital Capacity; forced expiratory volume in the 1 second (FEV1), Forced Expiratory Volume in the 1 second; FEV1/FVC= Forced Expiratory Volume in the 1 second / Forced Vital Capacity; GOLD: Global Initiative for Chronic Lung Disease; ISWT: Incremental Shuttle Walking Test; 6-minute walk test (6MWT): 6-Minute Walk Test
Our results showed reduced respiratory capacity and moderate associations between pulmonary function and respiratory muscle strength with performance at the 6MWT and ISWT, with a reduced performance being shown in submaximal and maximal exercise capacity as demonstrated by the regression models used
Summary
Chronic Obstructive Pulmonary Disease (COPD) is characterized by progressive airflow limitation associated with an inflammatory response to harmful particles and gases, mainly caused by smoking.[1] Inflammatory cells are active and there are increased plasma levels of proinflammatory cytokines in the systemic circulation that causes oxidative stress, which, in turn, will result in musculoskeletal disorders and reduced exercise capacity.[2] pulmonary dysfunction, systemic manifestations and increased dyspnea lead to progressive worsening in physical fitness and inactivity.[3,4] It is noteworthy that physical inactivity in COPD patients predisposes them to heart disease, increased risk of hospitalizations and higher mortality rate.[4,5]. The aim of the study was to evaluate the influence and the association of respiratory variables on exercise capacity in COPD patients. Methods: A cross-sectional study evaluated 39 COPD patients to obtain forced expiratory volume in one second (FEV1) and forced vital capacity (FVC). Santa Cruz do Sul, 2018 Out-Dez;8(4):385-391. [ISSN 2238-3360]
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