Abstract
Inflammation and platelet activation play a central role in the initiation and progression of the atherosclerosis process. The Platelet-to-lymphocyte ratio (PLR) is a new prognostic marker in coronary artery disease. The PLR is a significant independent predictor of long-term mortality after none-ST elevated myocardial infarction (NSTEMI). We aimed to evaluate the relationship between PLR and no-reflow (NR) in patients with NSTEMI.
Highlights
Inflammation and platelet activation play a central role in the initiation and progression of the atherosclerosis process
We aimed to evaluate the relationship between Platelet-to-lymphocyte ratio (PLR) and no-reflow (NR) in patients with none-ST elevated myocardial infarction (NSTEMI)
This study showed that PLR is an independent predictor of NR in patients with NSTEMI
Summary
Inflammation and platelet activation play a central role in the initiation and progression of the atherosclerosis process. The Platelet-to-lymphocyte ratio (PLR) is a new prognostic marker in coronary artery disease. The PLR is a significant independent predictor of longterm mortality after none-ST elevated myocardial infarction (NSTEMI). We aimed to evaluate the relationship between PLR and no-reflow (NR) in patients with NSTEMI. Acute coronary syndrome (ACS) is a leading cause of death worldwide, and patients with none-ST elevation myocardial infarction (NSTEMI) have a higher long-term mortality risk due to the prevalence of comorbidities and multi-vessel coronary artery disease (CAD) [1]. The Platelet to lymphocyte ratio (PLR) was introduced as a potential marker for excess thrombotic activity [6] and inflammation in cardiac disorders [7]. The PLR has recently emerged as a significant predictor of major adverse consequences in cardiovascular disease [8].
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