Abstract

Piscine mycobacteriosis is a fatal fish illness that affects a variety of species globally. It affects over 200 species of freshwater and marine fish. Several species of Mycobacterium are responsible among them Mycobacterium marinum is the comment. It also affects humans when exposed to contaminated water. In fishes, the symptoms include eroded fins, body surface coated with heavy mucus, changing pigmentation, swelling of abdomen, ulcerative dermal necrosis, and scale loss. In humans, the infection is classified into three clinical groups. Type I is a self-limiting, verruca lesion. Type II is single or numerous subcutaneous granulomas in the presence or absence of ulceration. Type III is deep infections of the tenosynovium, bones, bursa, or joints, resulting in tenosynovitis, osteomyelitis, and septic arthritis. The diagnosis is made by Ziehl-Neelsen acid-fast staining, culture, biochemical reaction, and PCR being the most reliable approach. Piscine mycobacteriosis is treated by antibiotics and vaccination has been considered for its long-term prevention in order to reduce morbidity and mortality. Morgellons disease (MD) is a filamentous dermopathy in which lesions with strange filamentous inclusions appear out of nowhere. Furthermore, formication may accompany dermopathy. The identification of Borrelia spirochetes directly in Morgellons disease patient specimen is constant and repeatable when sensitive and precise detection techniques are utilized. It has been diagnosed by microscopy, histology and molecular diagnostic techniques which are highly sensitive and specific. Morgellons disease is still a myth therefore its treatment is evolving, up to date it has been treated symptomatically.

Highlights

  • Piscine mycobacteriosis is a zoonotic illness that affects both freshwater and marine fish globally

  • Healthcare practitioners commonly and incorrectly identify the illness as a type of delusional infestation (DI) or the heritage names delusional parasitosis (DP) and delusions of parasitosis (DOP) due to the false idea that the fibers are generated from textiles [5]

  • The etiological factor for piscine mycobacteriosis is Mycobacterium species; more than 20 strains of Mycobacterium species have been found in fish

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Summary

Introduction

Piscine mycobacteriosis (fish tuberculosis) is a zoonotic illness that affects both freshwater and marine fish globally. More than 20 strains of Mycobacterium species have been found in fish, the pathogenesis of the majority of them is unclear [1]. Fish tuberculosis is caused by Mycobacterium marinum, and Mycobacterium fortuitum [2]. Mycobacterium marinum is an opportunistic infection responsible for tuberculosis-like disease in fish and can infect people when damaged skin is exposed to a polluted aquatic environment. Borrelia spirochetes causative agent of Lyme disease such as B. sensu lato (Bbsl), Bb sensu stricto (Bbss), Relapsing Fever Borrelia (RFB) and Borrelia burgdorferi (Bb) species, have been found in Morgellons disease patient’s bodily fluids and/or tissue samples. Other infections found in Morgellons disease patient’s tissues include Helicobacter pylori (Hp), Treponema denticola, Bartonella henselae, and Rickettsiae species, suggesting that these pathogens may be involved in the development of the dermopathy [6]. Some other Borrelia species have been found in Morgellons disease patients’ skin samples such as Borrelia garinii, Borrelia hermsii and Borrelia miyamotoi [7]

Epidemiology
History and Classification
Etiology
Clinical Signs and Symptoms
Methodology
Treatment
History and Background
Clinical Features
Classification
Findings
Conclusion
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