Abstract

IntroductionAs the world's population ages, the prevalence of cognitive impairment associated with age increases. This increase is particularly pronounced in Asia and South-America. The objective of this study was to investigate separately the longitudinal association of physical activity and cognitive function in; older adults in Mexico and South Korea. Materials and MethodsThis is a secondary analysis of two surveys, The Mexican Health and aging Study (MHAS) (n = 5853) and Korean Longitudinal Study of aging (KLoSA) (n = 5188), designed to study the aging process of older adults living in Mexico and South Korea. Participants older than 50 years were selected from rural and urban areas achieving a representative sample. Physical activity was assessed using self-report. Cognition was assessed using Cross-Cultural Cognitive Examination (CCCE) and Minimental state examination (MMSE) in Mexico and South Korea respectively. Here we investigate the longitudinal association between physical activity and cognition during 3 years for MHAS and 4 years for KLoSA using multiple linear regression analyses. ResultsThe prevalence of physical activity was 40.68 % in MHAS and 35.57 % in KLoSA. In the adjusted longitudinal multivariate analysis, an independent association was found between physical activity and MMSE score OR 0.0866 (CI 0.0266-0.1467 p-value 0.0047) in the Korean older adults, while there was no significant association in MHAS. ConclusionsPhysical activity could have a protective effect on the cognitive decline associated with aging in the Korean population.

Highlights

  • As the world's population ages, the prevalence of cognitive impairment associated with age increases

  • Materials and Methods: This is a secondary analysis of two surveys, The Mexican Health and aging Study (MHAS) (n = 5853) and Korean Longitudinal Study of aging (KLoSA) (n = 5188), designed to study the aging process of older adults living in Mexico and South Korea

  • We investigate the longitudinal association between physical activity and cognition during 3 years for MHAS and 4 years for KLoSA using multiple linear regression analyses

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Summary

Introduction

As the world's population ages, the prevalence of cognitive impairment associated with age increases. The objective of this study was to investigate separately the longitudinal association of physical activity and cognitive function in; older adults in Mexico and South Korea. Materials and Methods: This is a secondary analysis of two surveys, The Mexican Health and aging Study (MHAS) (n = 5853) and Korean Longitudinal Study of aging (KLoSA) (n = 5188), designed to study the aging process of older adults living in Mexico and South Korea. As the world population ages, the prevalence of age-associated cognitive decline and dementia increases (Orgeta, Mukadam, Sommerlad, & Livingston, 2019). This is detrimental for the affected individuals and bears a major emotional, physical and economic burden on the health care providers and society. Skeletal muscles can release myokines that induce angiogenesis and promote neuroplasticity, especially in the hippocampus and medial temporal lobe (Iizuka, Machida, & Hirafuji, 2014)

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