ASSOCIATION BETWEEN PERIRENAL ADIPOSE TISSUE AND OTHER VISCERAL FAT DEPOTS IN PATIENTS WITH ABDOMINAL OBESITY

Abstract

Objective: Perirenal adipose tissue is the fat pad surrounding the kidneys. It is proposed as new risk factor for cardiovascular diseases. The aim of study to assess the correlation between perirenal adipose tissue (PAT) volume with waist circumference, abdominal adipose tissue volume and epicardial adipose tissue (EAT) volume and thickness in patients with abdominal obesity. Design and method: The study included 104 patients (37,5% - men, 62.5% - women), mean age 38.59 ± 6.09 years with abdominal obesity (waist circumference (WC) > 80 cm in women and > 94 cm in men), without cardiovascular diseases and diabetes mellitus. Abdominal adipose tissue volume (visceral and subcutaneous), EAT volume and perirenal adipose tissue (PAT) volume were measured by multislice computed tomography (ToshibaAquillion 640, Japan). EAT thickness was determined using transthoracic echocardiography (Vivid 7, Vivid 9 (GE Healthcare, USA)) on the free wall of the right ventricle from both parasternal long- and short-axis views at end-systole and end-diastole during three cardiac cycles. Results: The mean BMI was 32,3 ± 5,3 kg/m2, the mean WC was 105,9 ± 13,6 cm. In all patients, the mean visceral abdominal adipose tissue volume was 144,9 ml (range: 36,2 to 367,2 ml), the mean subcutaneous adipose tissue volume was 225,3 ml (range: 101,8 to 425,3 ml), the mean PAT volume was 116,0 ml (range: 28,2 to 311,7 ml), the mean EAT volume was 90,1 ml (range: 21,0 to 284,0 ml). PAT volume was significantly correlated with intraabdominal visceral adipose tissue volume (r = 0,58; p < 0,05). There are no association between PAT and subcutaneous adipose tissue volume (r = 0,02; p < 0,05). PAT volume has strong correlation with EAT volume (r = 0,43; p < 0,05), EAT thickness (at end-systole r = 0,36; p < 0,05, at end-diastole r = 0,40; p < 0,05). Conclusions: This study showed strongly association between PAT with intraabdominal visceral adipose tissue, EAT. It confirms that PAD is one of the ectopic visceral fat depots and could indicated visceral obesity