Association between parity and ovarian reserve in reproductive age women

Abstract

ObjectiveA number of factors affect ovarian reserve. In this study, we investigate the association between parity and ovarian reserve in reproductive age women. Materials and methodsThis cross-sectional study was conducted on 186 women aged 20–35 years. The participants were divided into two main groups. Group A (n=93) included women with at least one parity (pregnancy after 28 weeks), while group B (n=93) included women with no history of pregnancy. We evaluated the following factors related to ovarian reserve: follicle-stimulating hormone (FSH), ovarian antral follicles, anti-Müllerian hormone (AMH), and ovarian volume. ResultsA total of 186 women with a mean age of 27.83±4.49years enrolled in this study. There was a difference in mean AMH between the nulliparous (2.53±1.90ng/ml) and multiparous (3.54±1.42ng/ml) groups (p<0.001). FSH levels were from 5.27±1.8mIU/mL in nulliparous women to 5.01±1.9mIU/mL in multiparous women, which did not significantly differ (p=0.36). Antral follicles and ovarian size in multiparous women increased significantly (p<0.001). ConclusionParity has a significant association with higher levels of ovarian reserve markers.