Association between parity and macrosomia in Shaanxi Province of Northwest China

Fangliang Lei,Yijun Kang,Yuan Shen,Lili Zhang,Hong Yan,Shaonong Dang,Pengfei Qu,Baibing Mi,Yaling Zhao

doi:10.1186/s13052-020-0784-x

Abstract

ObjectiveTo explore the relationship between parity and macrosomia and provide the necessary reference for the maternal and children health service.MethodA cross-sectional epidemiological survey with the purpose to assess the birth outcomes was conducted in Shaanxi province, China.ResultsThe incidence of macrosomia in multiparas was higher than that in primiparas. Univariate analysis showed that maternal age < 25 years, peasant/housework, living in rural areas and female infants were the protective factors of macrosomia. The possibility of having a macrosomic infant also increased with gestational age, maternal education level, household wealth index, living in Central Shaanxi and gestational diabetes. The generalized linear mixed models represented the association between parity and macrosomia. After adjusting for statistically significant factors in univariate analysis from model 1 to model 3, the risk of being born macrosomia was 1.26 times higher for a multipara compared to that for a primipara.ConclusionsPresent study indicated parity of two children was associated with increased risk for macrosomic births compared with parity of one child. Compared to primiparas, multiparas should far strengthen the pre-pregnancy education and the guidance during pregnancy to control pre-pregnancy body mass index and pregnancy weight, and keep the appropriate exercise and balanced diet.

Highlights

Birth weight (BW) is an important indication of mothers’ and neonates’ nutritional status, and may be the important determinant of infant’s survival and future health, Lei et al Italian Journal of Pediatrics (2020) 46:24 growth, and development [1]
We found that parity was related to the occurrence of macrosomia
The incidence of macrosomia of multipara was higher than primipara, and the difference was statistically significant

Summary

Introduction

Birth weight (BW) is an important indication of mothers’ and neonates’ nutritional status, and may be the important determinant of infant’s survival and future health, Lei et al Italian Journal of Pediatrics (2020) 46:24 growth, and development [1]. Macrosomia prevalence in developed countries is between 5 and 20%, an increase of 15 to 25% has been reported in the past decades. With rapid economic growth in China in the past three decades, investments in education, healthcare and sanitation have increased . Chinese national health services survey showed that birth weight increased from 3186 g in 1993 to 3284 g in 1998 and to 3307 g in 2003 [5]. A rapid increase in rate of macrosomia has been reported in China. One study about secular trends of macrosomia in southeast China reported an increase from 6.0% in 1994 to 7.8% in 2005 [2]. In Shanghai, the rates of macrosomia increased by 50% between 1989 and 1999

Methods

Results

Discussion

Conclusion