Abstract
Opioids-induced esophageal dysfunction has been described with characteristic manometric patterns, but the population burden of dysphagia attributable to opioid use remains unclear. National Ambulatory Medical Care Survey (NAMCS) from 2008-2018 was used to assess the relationship between opioid use and outpatient visits for dysphagia. After controlling for potential confounders there were no significant difference in ambulatory visits for dysphagia between opioid users and non-users (adjusted odds ratio=0.98, confidence interval: 0.59-1.65). No correlation between opioid use and ambulatory visits for dysphagia was found in a nationwide sample. Opioid-related manometric changes may be clinically relevant only in a small proportion of patients.
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