Abstract

Mannheimiosis or pneumonic pasteurellosis commonly occurs in small ruminants. Mannheimiosis is caused by Mannheimia haemolytica (M. haemolytica) a Gram-negative coccobacillus producing acute febrile and infectious condition resulting in death of animal if not diagnosed and treated promptly. M. haemolytica serotype A2 is a commensal of the nasopharynx, gaining access to the lungs when host defenses are compromised by stress or infection in small ruminants. Till date, there is a vast literature and research that has been conducted on the pathogenesis of M. haemolytica invariably on respiratory system and its related immune system and mechanisms. From the clinical point of view, infection or diseases involving vital organs will systemically affect the production and performance of the infected animal. Therefore, there is a huge gap of knowledge and research to answer the question whether there is any association between M. haemolytica infection with reproductive physiology and performance in small ruminants and how it affects the productivity level. This review will explore the possibilities of involvement and new potential research to be carried out to determine the involvement of male and female reproductive system with M. haemolytica infection among small ruminants.

Highlights

  • Mannheimiosis or pneumonic pasteurellosis continues to be the principal constraint to the progression of small ruminant production in the tropics

  • A study was conducted by Abdullah et al [32] to observe the pathological alterations in pituitary glands of animals challenged with P. multocida type B:2 and its LPS and the results revealed significant cellular changes such as edema, hemorrhage, degeneration, and necrosis in pituitary glands of the challenged animals

  • Further research is warranted in this area, in which the findings would contribute to the understanding one of the reproductive disorders in small ruminants that may be due to M. haemolytica and its LPS endotoxin infection

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Summary

Introduction

Mannheimiosis or pneumonic pasteurellosis continues to be the principal constraint to the progression of small ruminant production in the tropics. The pathogenesis of small ruminant pneumonia in contributing to the reproductive failure in female animals is still in a gray area and the pathogenesis could still not be drafted as no detailed studies were designed to look into this area.

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