Association between Lymphocyte-to-Monocyte Ratio and Survival in COVID-19 Infected Patients

Abstract

Early identification of patients who may develop into clinical deterioration is necessary to prevent complications and death from COVID-19. This research aims to determine the association between lymphocyte-to-monocyte ratio (LMR) and survival in Coronavirus disease-2019 (COVID-19) patients. This study used a retrospective cohort design. We collected survival data retrospectively by tracing medical records to gather data on demographic, clinical, and laboratory characteristics. Mann-Whitney U test was used to determine the difference in LMR values in the survivor and non-survivor groups. A total of 502 subjects were involved in this study. The LMR value was significantly lower in the non-survivors group compared to the survivors group (p=0.001). We found an adjusted odds ratio (OR) of LMR of 3.62; 95% confidence interval (CI) 1.92-14.25; p=0.046). LMR can reflect the disease severity and can be used to predict prognosis.