Abstract
Objective: This study was done to determine the association between lipid levels and diabetic Indices in confirm patients of myocardial infarction with versus without diabetes mellitus type II. Methodology: Two hundred acute myocardial infarction having ST-segment elevation patients with diabetes mellitus type II and without diabetes mellitus type II were enrolled. Lipid levels and diabetic indices were measured, and the correlations among them were analyzed. Results: Positive correlations were found between triglycerides and fasting blood sugar, low density lipoprotein and Insulin when compared among myocardial infarction patients. Comparison among myocardial infarction patients with diabetes mellitus type II and without diabetes mellitus type II, negative correlations were found between triglycerides and glycosylated hemoglobin (HbA1C), low density lipoprotein and glycosylated hemoglobin, glycosylated hemoglobin and Insulin. Conclusion: Correlations between lipid levels and diabetic indices when compared were found to be Positive in myocardial infarction patients only and Negative when compared between myocardial infarction patients with diabetes mellitus type II and without diabetes mellitus type II.
Highlights
The presentation of acute myocardial infarction (AMI) is attributed to interruption in coronary artery blood supply on the basis of diseases related to coronary artery, which causes serious and persistent ischemia.[1]
Positive correlations were found between triglycerides and fasting blood sugar, low density lipoprotein and Insulin when compared among myocardial infarction patients
Comparison among myocardial infarction patients with diabetes mellitus type II and without diabetes mellitus type II, negative correlations were found between triglycerides and glycosylated hemoglobin (HbA1C), low density lipoprotein and glycosylated hemoglobin, glycosylated hemoglobin and Insulin
Summary
The presentation of acute myocardial infarction (AMI) is attributed to interruption in coronary artery blood supply on the basis of diseases related to coronary artery, which causes serious and persistent ischemia.[1]. Coronary artery diseases risk factors include old age, high blood pressure, cigarette smoking, hyperlipidemia, diabetes mellitus, inflammatory reaction and others.[4] Diabetes Mellitus Type II relates to dyslipidemia like decreased levels of HDLcholesterol, increased levels of ox-LDL, and increased levels of triglycerides.[5] If we compare prediabetic with non-diabetic’s the pre-diabetic’s have increased levels of TC, LDL-C, and TG and decreased levels of HDL-C which indicate an atherogenic pattern. In insulin resistance there is disturbance in the levels of f VLDL, LDL, and HDL.[6] There is evidence in numerous studies; morbidity due to DMT2 is associated with cardiovascular diseases, due to dyslipidemia which causes change in the size or density of LDL.[7,8]
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