Abstract
The aim of this study was to investigate the distribution characteristics of GerdQ results in a Chinese population and the association between lifestyle and GerdQ scores. Among the 37 442 individuals enrolled from September 2009 to March 2016, 7 449 (19.89%) had a GerdQ score of ≥8 points and 29 993 (80.11%) had a GerdQ score of <8 points. The percentage of men with suspected GERD was significantly higher than the percentage of women with suspected GERD (χ2 = 111.571, P ≤ 0.001), and the prevalence of GERD was higher in the young and middle-aged populations than in the elderly population. The prevalence of GERD increased gradually with weight gain (χ2 = 145.227, P ≤ 0.001). With regard to lifestyle, the prevalence of GERD in the subjects who smoked (χ2 = 119.361, P ≤ 0.001), consumed alcohol excessively, lacked physical activity (χ2 = 86.916, P ≤ 0.001), and had an excessive intake of oil, meat, fish, and eggs showed an ascending trend (χ2 = 105.388, P ≤ 0.001). In contrast, an adequate intake of vegetables (≥300 g/d) and fruit (≥200 g/d) was associated with a significantly lower incidence of GERD. Suspected GERD is very common in individuals undergoing health examinations. Unhealthy lifestyles are closely related to the high incidence of suspected GERD. GerdQ scores can play a role in screening for GERD.
Highlights
Gastroesophageal reflux disease (GERD) refers to the symptoms and complications caused by the backflow of gastric content into the oesophagus, mouth, or lungs [1]
Among the 37 442 subjects enrolled in this study, 7 449 (19.89%) had a gastroesophageal reflux disease questionnaire (GerdQ) score of ≥8 points and 29 993 (80.11%) had a GerdQ score of
According to the GerdQ scores, the subjects were divided into two groups: the suspected GERD group and the non-GERD group
Summary
Gastroesophageal reflux disease (GERD) refers to the symptoms and complications caused by the backflow of gastric content into the oesophagus, mouth (including the throat), or lungs [1]. Reflux oesophagitis (RE) occurs when the oesophageal mucosa is damaged by acid (alkali) reflux. According to the results of endoscopic examination, GERD can be divided into nonerosive gastroesophageal reflux disease with negative endoscopic examination (NERD) and reflux oesophagitis with positive endoscopic examination. The complications of GERD may be the oesophageal mucosa break, ulcer or peptic stricture, Barrett’s oesophagus (BE), and even oesophageal carcinoma [2]. The common symptoms of GERD include heartburn, regurgitation, nausea, belching, and angina-like retrosternal chest pain. Many patients may present with atypical symptoms, such as abnormal sensation of the pharynx, chest tightness, shortness of breath, cough, and asthma, which often led to missed diagnosis and misdiagnosis [3]
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