Abstract
The association between insomnia and metabolic syndrome remains unclear, especially among different-aged groups. A cross-sectional study with 8017 participants was performed to identify whether insomnia was associated with metabolic syndrome or not. Demographic characteristics, lifestyles and other risk factors were collected using a predesigned, semi-structured, self-administered questionnaire, and physical examinations were conducted by certificated community physicians. Insomnia was not independently associated with metabolic syndrome across all subjects; however, the association between insomnia and metabolic syndrome was statistically significant in the male group (odds ratio (OR): 1.35, 95% confidence interval (CI): 1.02–1.77) and the middle-aged group (OR: 1.40, 95% CI: 1.09–1.79) but not in the female group, the young adult group or the older group. Analyses of the individual components of metabolic syndrome revealed that insomnia was independently associated with raised blood pressure (OR: 1.24, 95% CI: 1.05–1.43) and low high-density lipoprotein cholesterol (HDL-c) (OR: 1.16, 95% CI: 1.01–1.33). Insomnia was also independently associated with the severity of metabolic abnormalities (OR: 1.17, 95% CI: 1.03–1.32). This study demonstrates an independent association between insomnia and metabolic syndrome in males and middle-aged participants, which suggests that treatment for insomnia will contribute to the prevention of metabolic syndrome in males and the middle-aged population.
Highlights
Insomnia is a subjective feeling of difficulty initiating sleep, difficulty maintaining sleep, waking up too early, non-restorative sleep or poor quality of sleep[11]
The present study aimed to evaluate the association between insomnia and metabolic syndrome in a Chinese adult population, and, to explore the association among participants stratified by age and sex, considering that both metabolic syndrome and insomnia are associated with age and gender[8, 11, 17]
Based on the large population-based sample, this study showed that there was an independent association between insomnia and metabolic syndrome in males and in middle-aged people; insomnia was associated with raised blood pressure and low HDL-c in all participants
Summary
Insomnia is a subjective feeling of difficulty initiating sleep, difficulty maintaining sleep, waking up too early, non-restorative sleep or poor quality of sleep[11]. Some studies have shown that insomnia is associated with metabolic syndrome[16,17,18]. Several studies have shown that insomnia is not related to metabolic syndrome[19,20,21]. It is not yet conclusive whether insomnia is associated with metabolic syndrome or not. We hypothesized that insomnia may be associated with metabolic syndrome in Chinese populations. The present study aimed to evaluate the association between insomnia and metabolic syndrome in a Chinese adult population, and, to explore the association among participants stratified by age and sex, considering that both metabolic syndrome and insomnia are associated with age and gender[8, 11, 17]
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