Association between hyperuricemia and coronary artery disease severity among patients undergoing coronary angiography

Abstract

Aim: To determine the association between hyperuricemia and coronary artery disease severity among patients undergoing coronary angiography. Methods: This study was conducted at multi centers including Al- Aleem Medical College (Gulab Devi Teaching Hospital) Lahore and Fatima Memorial Hospital Lahore in the duration from December, 2022 to May, 2023. Total 180 patients were presented with Coronary Artery Disease, Coronary angiography was performed to determine the presence of coronary artery disease, with patients having luminal stenosis of greater than 50% in at least one of the coronary arteries. Relation between hyperuricemia and coronary artery disease was assessed using Chi Square test keeping P < 0.05 as significant. Results: The mean age was 49.59±6.11 years. The frequency of hyperuricemia was 120 (66.7%), around 32.3% patients had mild CAD, about 37.2% patients had moderate CAD while 30.6% patients had severe CAD. We found a significant association between hyperuricemia and severity of CAD. Conclusion: We conclude that hyperuricemia is significantly associated with the severity of coronary artery disease (CAD).