Abstract

BackgroundHypertension and musculoskeletal disorders are highly prevalent in adult populations. The objective of this study was to investigate the association between hypertension and prevalence of low back pain (LBP) and osteoarthritis in Koreans.MethodsA total 17,128 participants (age ≥20 years) who answered low back pain and osteoarthritis items in the 4th Korean National Health and Nutrition Examination Survey (2007–2009) were analyzed. Odds ratios were calculated using logistic regression and were adjusted for age, sex, income level, education, occupation, BMI, smoking status, alcohol consumption, and physical activity.ResultsLifetime prevalence of LBP in hypertensive subjects was 34.4%, and that of osteoarthritis 26.2%. LBP prevalence was significantly lower in hypertensives (fully adjusted OR 0.79; 95% CI 0.70–0.90), and both LBP and osteoarthritis prevalence was significantly lower in participants with systolic blood pressure ≥140mmHg than those with <120mmHg (fully adjusted OR 0.81; 95% CI 0.70–0.94, and 0.81; 95% CI 0.68–0.96, respectively). Prevalence of LBP in subjects with diastolic blood pressure ≥90mmHg was also significantly lower than those with <80mmHg (fully adjusted OR 0.73; 95% CI 0.63–0.85). LBP and osteoarthritis prevalence did not differ by systolic or diastolic blood pressure interval in respondents taking antihypertensive medication. LBP and osteoarthritis prevalence increased with longer hypertension duration (fully adjusted p for trend 0.028, and 0.0008, respectively).ConclusionsHypertension showed an inverse relationship with LBP and osteoarthritis prevalence, which may be ascribed to hypertension-associated hypalgesia, and antihypertensive medication intake and longer hypertension duration attenuated this association.

Highlights

  • Low back pain (LBP) continues to be one of the most common musculoskeletal disorders causing disability, severe pain, and extended sick leave at substantial personal and social expense [1], and an estimated 70–80% of adults suffer from low back pain (LBP) at some point of their lives [2]

  • LBP prevalence was significantly lower in hypertensives, and both LBP and osteoarthritis prevalence was significantly lower in participants with systolic blood pressure 140mmHg than those with

  • Prevalence of LBP in subjects with diastolic blood pressure 90mmHg was significantly lower than those with

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Summary

Introduction

Low back pain (LBP) continues to be one of the most common musculoskeletal disorders causing disability, severe pain, and extended sick leave at substantial personal and social expense [1], and an estimated 70–80% of adults suffer from LBP at some point of their lives [2]. Cardiovascular disease risk factors such as obesity, smoking, and serum lipid levels have been implicated with LBP and osteoarthritis through the atherosclerosis hypothesis. There are reports that high serum cholesterol and triglyceride levels result in higher LBP occurrence [9]. Hypertension and musculoskeletal disorders are highly prevalent in adult populations. The objective of this study was to investigate the association between hypertension and prevalence of low back pain (LBP) and osteoarthritis in Koreans

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