Abstract

Serum from a multitransfused patient with bladder papilloma was examined. The serum contained anti-Kell as well as polyspecific, cytotoxic HLA antibodies and HLA-associated haemagglutinins. The HLA haemagglutinins were demonstrated by the Auto Analyzer method and reacted predominantly with red blood cells (RBC) from HLA-A28-positive individuals, and were distinctly weaker with all other test cells. Survival studies with 51Cr-RBC from an HLA-A28-positive, Kell-negative donor with strong A28 RBC reactivity were performed. A small component of the RBC showed clearly reduced survival time, while the main component showed nearly normal survival.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.